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Real Madrid, sitting 9th in the league, welcome 24th-placed Benfica in a crucial Champions League encounter.
Underdogs Bodø / Glimt pull off a shock 2-1 victory over Inter in the Champions League, dealing a blow to the Italian giants' European ambitions.
Fifth-placed Manchester United look to close the gap on the top four as they visit ninth-placed Everton in a crucial Premier League clash.
Arsenal thrash Tottenham 4-1 in a dominant display, cementing their position at the top of the Premier League table.
Bayer 04 Leverkusen travel to the capital to face a struggling FC Union Berlin side as they look to close the gap in the Bundesliga table.
Osasuna look to capitalize on their recent form and pull off a shock result against the rampant La Liga leaders Real Madrid.
Second-placed Manchester City welcome 10th-placed Newcastle United in a crucial Premier League match.
League leaders Galatasaray face off against 14th-placed Konyaspor in a crucial Super Lig clash.
Nottingham Forest deliver a dominant performance, securing a crucial 3-0 win over struggling Fenerbahçe in the Europa League.
Wolverhampton Wanderers staged a remarkable comeback to hold Premier League leaders Arsenal to a 2-2 draw in a thrilling encounter.
Atlético Madrid, currently 14th in the league, face off against 19th-placed Club Brugge in a crucial Champions League encounter.
Galatasaray produce a stunning comeback to defeat Juventus 5-2 in a thrilling Champions League clash.